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It serves as the primary substrate for glutathione peroxidase (GPx) enzymes that neutralise hydrogen peroxide and lipid hydroperoxides, and for glutathione S-transferases (GSTs) involved in xenobiotic detoxification

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Concerning the inhibition of NF-kB activation, it occurs through the inhibition of degradation of its cytosolic dock IkB (inhibitor of NF-kB)