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What they found: Dose-dependent stimulation of type II collagen (up to 2.5× baseline at 100 nM) Stimulation of aggrecan (up to 1.8× baseline) Inhibition of MMP-13 by ~40 % Partial protection against IL-1β-induced matrix degradation Why it matters: It opened a completely new research area for AOD-9604 beyond lipolysis

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Last reviewed: April 2026 · Next scheduled review: October 2026 (FY2027 update) Ready to turn this knowledge into a credential