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In SMMC7721 and QGY7701 HCC cells, QUE promoted the expression of p53, inhibited Bcl-xl, and up-regulated the expression of Caspase-3/9, which enhanced the effect of DOX on promoting apoptosis (54)

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Cagrilintide is a synthetic 37-amino-acid acylated analog of the pancreatic hormone amylin, built on a pramlintide-like backbone with amino-acid substitutions and an N-terminal fatty-diacid (C20) modification via a gamma-glutamic acid linker