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This neurodegeneration is accompanied by the formation of characteristic Lewy bodies, which are intracellular inclusions composed largely of aggregated and misfolded α-synuclein (Balestrino and Schapria, 2020)

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It appears that the redox imbalance is an important etiologic contributor to insulin resistance, beta-cell dysfunction, and impaired glucose tolerance, all resulting in the development of type 2 diabetes (Wright et al