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BPC-157 as an Investigational Peptide Therapeutic: Biopharmaceutical Challenges, Formulation Strategies, and Translational Development Barriers

doi: 10.3109/10611860008996865 [Crossref] [ Google Scholar] O’Kane RL, Martinez-Lopez I, DeJoseph MR, Vina JR, Hawkins RA

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Genetical evidence from key studies confirms that eliminating GPX4 expression via genetic knockout in various cell types, or directly targeting its active site with small molecule inhibitors like RSL3, consistently and efficiently induces typical ferroptosis (Wang L