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Behavioral alterations from MPs exposure demonstrated clear dose-response and particle-specific patterns (Jiang et al., 2023) reported no alteration in neuropsychiatric symptoms at 12 weeks but observed clear effects after 24 weeks of exposure, supporting cumulative neurotoxicity

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The benzyl alcohol component is effective in limiting microbial growth, but concentrations are kept low (0.9%) to avoid altering compound stability under research conditions