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Autophagy and the Insulin-like Growth Factor (IGF) System in Colonic Cells: Implications for Colorectal Neoplasia

The subjects were divided into four treatment groups: [1] Control group (vehicle) Low-dose paraxanthine (equivalent to 25mg human dose) High-dose paraxanthine (equivalent to 100mg human dose) High-dose caffeine (equivalent to 100mg human dose) To assess cognitive function, the researchers employed the Morris water maze test , a well-established method for evaluating spatial learning and memory

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[DOI] [PMC free article] [PubMed] [Google Scholar] 311.Kansanen E., Bonacci G., Schopfer F.J., Kuosmanen S.M., Tong K.I., Leinonen H., Woodcock S.R., Yamamoto M., Carlberg C., Yla-Herttuala S., et al