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The protein is proteolytically cleaved to monomers that facilitate the aggregation of keratin intermediate microfibrils and collapse of the corneocyte cytoplasm (Steinert et al., 1981), after which the protein is further degraded to amino acids that aid in maintaining moisture in the stratum corneum (Harding and Scott, 1983

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A brief stinging sensation is a normal and manageable feature of GHK-Cu injection