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Similar SUA-lowering effects have been observed in a research investigations of the Mediterranean diet [58]

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In the early adhesion phase, immune defenses are active: neutrophils and M1 macrophages target bacteria via phagocytosis, oxidative bursts, increased antimicrobial peptides (AMPs↑), reactive oxygen species (ROS↑), and pro-inflammatory cytokines (IL-1β↑, IL-6↑, TNF-α↑) and chemokines