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For ipamorelin, it points to a published report of serious adverse events including death when given intravenously for gastric motility

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This interaction initiates the transcription of a broad array of cytoprotective genes, markedly enhancing the synthesis of intracellular glutathione and upregulating phase II detoxification and antioxidant enzymes, including glutathione S-transferases (GSTs) and heme oxygenase-1 (HO-1)