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In IFIGENIA study, researchers found that a regimen of three drugs (prednisone, azathioprine and acetylcysteine) preserved the better lung function than the two-drug regimen (azathioprine more prednisone) in IPF [126]

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Specifically, EGCG elevated the activities of antioxidant enzymes such as SOD and CAT, while concurrently reducing the levels of ROS and reactive nitrogen species (RNS), thereby preventing neuronal apoptosis (Kim et al