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Bile acids can trigger mitochondrial ROS generation in hepatocytes that in turn act to mediate the inactivation of PTPs, resulting in the activation of EGFR (90)

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3.6 Golgi apparatus: lipid modification and protein trafficking in axis regulation The Golgi apparatus modifies, sorts, and traffics proteins and lipids—functions that indirectly regulate the ferroptosis-immune-metabolic axis by influencing membrane composition and antioxidant defense (106)