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In colorectal cancer, they transfer complete mitochondrial genomes to surrounding epithelial cells, promoting TGF-β1-mediated tumor progression

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Recent studies have shown that insulin-regulated hepatic lipogenesis, but not gluconeogenesis, is mediated by stabilizing pleckstrin homology domain leucine-rich repeat protein phosphatase-2 (PHLPP-2), which terminates insulin-stimulated Akt activity [43,44]

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