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In addition, ginkgetin significantly decreased DDP-induced elevation of the binding of Nrf2 to the HO-1 promoter, thus decreasing HO-1 nuclear expression and reversing DDP-induced HO-1 nuclear translocation, ultimately enhancing the therapeutic effect of DDP ( 3.4 Saponin Ophiopogonin B (OP-B) is a saponin extracted from Ophiopogon japonicas (Thunb.) Ker Gawl

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