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[DOI] [PMC free article] [PubMed] [Google Scholar] 73.Mishkin A.D., Mapara M.Y., Barhaghi M., Reshef R

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Because the therapeutic potential of supplemental coenzyme Q 10 is limited to its capacity to restore electron transfer in a defective mitochondrial respiratory chain and/or to increase antioxidant defense, patients with secondary coenzyme Q 10 deficiency may fail to respond to supplementation (see Disease Treatment)