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Like JNK, the activity of ASK1 is low in nonstressed cells due to its sequestration via protein: protein interactions with GSTM1 (GSTM1: ASK1 complex), and/or thioredoxin (Trx:ASK1 complex) (Cho et al ., 2001

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While all of our top picks performed well from a safety perspective, that additional level of testing transparency helped Astaxanthin+ earn the edge