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Although thiamine deficiency is rare in developed countries, it can lead to severe neurological disorders, emphasizing the importance of adequate thiamine intake for optimal health and as treatment when administered promptly (6, 42)

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A 2025 pilot study infused up to 20 mg of BPC‑157 intravenously in 2 healthy adults and reported no adverse effects and no abnormal changes in heart, liver, kidney, thyroid, or blood‑glucose markers