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The study conducted by Lee and Padgett (2021) with intraarticular injections of BPC-157 did not report any adverse effects, although the screening for adverse events was not discussed at length [34]

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In animal and cell studies it upregulates growth hormone receptor expression, modulates nitric oxide signaling, promotes angiogenesis via VEGF pathways, and activates FAK-paxillin and Egr-1 pathways involved in fibroblast migration

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